Scientists and users debate which specific cannabis strain has the highest THC content https://cannabis-md.com/high-thc-strains-seeds/ but listed below are some of the most undeniably THC-potent strains for 2022. Grease Monkey This cannabis strain is an indica-dominant hybrid, and its parents are the potent strains Gorilla Glue (alternatively named Original Glue) and Cookies and Cream.