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Here are four possible , each taken from the known evolutionary playbook of :

1.A slide toward endemicity

2.Altered disease and symptoms

"In humans, SARS-CoV-2 has been found in the , , and central system. A new SARS-CoV-2 variant with redirected preference for new organs (organ tropism) could produce new Covid-19 signs and symptoms."

3.Emergence of a new recombinant coronavirus

4.Exploitation of antibodies

"In this worrisome scenario, SARS-CoV-2 evolves to not only evade its human host’s immune response but to actively exploit it. The successive major variants of SARS-CoV-2 so far show that the evolution of the virus helps evade the system. But some coronaviruses take evasion to the level of exploitation."

statnews.com/2022/02/16/corona

STATCoronaviruses are 'clever': Evolutionary scenarios for the future of SARS-CoV-2By Patrick Skerrett