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#epigenetics

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Moritz Bartl

"There is a growing understanding that mental illness has a crucial physical component and may cause disturbances of mind and body which strongly emphasizes a crucial role of psychotherapy focused on early stressful experiences mainly during critical developmental periods including prenatal and perinatal traumas."

"#epigenetics […] will likely be one of the most important areas of scientific research."

Janov, A. Epigenetics and Primal Therapy. Act Nerv Super 57, (2015). doi.org/10.1007/BF03379941

SpringerLinkEpigenetics and Primal Therapy - Activitas Nervosa SuperiorEpigenetics is focused on the study of how experience changes an individual’s genetic expression, previously considered inalterable. Recent pioneering research indicates that epigenetics is revolutionizing the study of mental health and challenging the belief that DNA is destiny. Moreover, in terms of the history of science, the new developments augur the convergence of previously distinct fields, psychology and biology. There is a growing understanding that mental illness has a crucial physical component and may cause disturbances of mind and body which strongly emphasis a crucial role of psychotherapy focused on early stressful experiences mainly during critical developmental periods including prenatal and perinatal traumas.
Levka

#epigenetics

"A stressful life can leave marks on our genetic code, some of which can even be passed on to our children. A study now reveals how the biological impact of trauma on a mother persists long after the violent acts themselves have passed.

The international team of researchers demonstrate the physical mechanisms behind intergenerational trauma in humans, explaining why people with a family history of adversity are more prone to mental health conditions like anxiety and depression, despite not having experienced the adverse events themselves."

sciencealert.com/violence-leav

ScienceAlert · Violence Leaves Its Mark on Our Genes For Generations, Study FindsA stressful life can leave marks on our genetic code, some of which can even be passed on to our children.
Karl Theodor

@SheDrivesMobility danke für die mutigen Worte. Ich habe einmal #HeribertPrantl geschrieben, dass sich Geschichte wiederholt. ER meinte damals: NEIN. Leider sehe ich den Faschismus weltweit wieder hervor kommen. Wie der #Faschismus seinen Weg nehmen kann, dazu habe ich mir Gedanken gemacht und bin zu dem Ergebnis gekommen, [These] dass wir wohl vielfach traumatisierte Wesen sind und das sich diese "Neurotisierung" eben auswirkt. siehe #Janov #epigenetics cigognenews.blogspot.com/2016/

Januar 2025 CRISPR_rEvolution Faschismus Protrait Art Janov Janov's Reflections on the Human Condition: The Simple Truth is Revolutionary Articles on Primal Therapy, psychogenesis, causes of psychological traumas, brain development, psychotherapies, neuropsychology, neuropsychotherapy. Discussions about causes of anxiety, depression, psychosis, consequences of the birth trauma and life before birth. Thursday, April 14, 2016 What Happens When You Can't Feel? How Fascism Gets Its Start I will use myself as an example. I worked in the meat-packing house when I was young. And once a month we played “the greased pig. “ We took a greased pig to the park and we stood around in a circle and dove on him to try to pin him down. The winner was the guy who could pin him down for 2 minutes. It is abhorrent to me now and unthinkable and cruel. Why? ... https://cigognenews.blogspot.com/2016/04/what-happens-when-you-cant-feel-how.html
ALT
ISOGG

“Overall, the original ‘malaria hypothesis’ of Haldane that diseases such as thalassemia are polymorphisms with an advantage to heterozygotes in malarial environments has been proven correct.” #dna #isogg #malaria #epigenetics #population #genetics #geneadons

nature.com/articles/hdy201116

NaturePopulation genetics of malaria resistance in humans - HeredityThe high mortality and widespread impact of malaria have resulted in this disease being the strongest evolutionary selective force in recent human history, and genes that confer resistance to malaria provide some of the best-known case studies of strong positive selection in modern humans. I begin by reviewing JBS Haldane's initial contribution to the potential of malaria genetic resistance in humans. Further, I discuss the population genetics aspects of many of the variants, including globin, G6PD deficiency, Duffy, ovalocytosis, ABO and human leukocyte antigen variants. Many of the variants conferring resistance to malaria are ‘loss-of-function’ mutants and appear to be recent polymorphisms from the last 5000–10 000 years or less. I discuss estimation of selection coefficients from case–control data and make predictions about the change for S, C and G6PD-deficiency variants. In addition, I consider the predicted joint changes when the two β-globin alleles S and C are both variable in the same population and when there is a variation for α-thalassemia and S, two unlinked, but epistatic variants. As more becomes known about genes conferring genetic resistance to malaria in humans, population genetics approaches can contribute both to investigating past selection and predicting the consequences in future generations for these variants.
MPI Immunobiology Epigenetics

Hello! Hey Fediverse, once again. We are the Max Planck Institute of #Immunobiology and #Epigenetics. And we had to change our server.

Our community seems not really into this platform. Yet, we still believe that embracing open science with mastodon is important. For the time being, we investigate what to do with this account in the future and we will continue to cross-post our content.

Stay with us: ie-freiburg.mpg.de
#introduction #neuhier #sciencemastodon

SPQR

This memory arises because the experience of obesity leads to changes in the epigenome — a set of chemical tags that can be added to or removed from cells’ DNA and proteins that help to dial gene activity up or down. For fat cells, the shift in gene activity seems to render them incapable of their normal function.
#nutrition #genetics #obesity #physiology #epigenetics #science nature.com/articles/d41586-024

www.nature.comFat cells have a ‘memory’ of obesity — hinting at why it’s hard to keep weight offLong-lasting changes to the cells’ epigenome are linked to a decline in their function.
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